DDR biomarker and PARP/ATR inhibitor response pipeline. Full GDSC v17 mutations + CNV + MSI + tissue context. POC: Talazoparib HRD Spearman ρ=+0.12 (p=3e-4, n=912); per-drug CV AUC 0.68–0.77.
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Updated
Apr 10, 2026 - Python
DDR biomarker and PARP/ATR inhibitor response pipeline. Full GDSC v17 mutations + CNV + MSI + tissue context. POC: Talazoparib HRD Spearman ρ=+0.12 (p=3e-4, n=912); per-drug CV AUC 0.68–0.77.
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